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- W2347676543 abstract "Objective To explore the mechanism of benign biliary stricture.Methods A model of trauma of bile duct was established in dogs and then repaired.The expression and distribution of MΦ,TGF-β_1 and α-SMA in tissues at different time phases of the healing process were studied after the operation with immunohistochemical SP staining.Results High expression of MΦ,TGF-β_1 and α- SMA were observed in the healing process and lasted for a long time.MΦ staining was found in the in- trinsic layer under mucosa,TGF-β_1 staining in the granulation tissue,fibroblasts and endothelial cells of blood vessels while α-SMA staining in the myofibroblasts.Conclusions The high expression of MΦ,TGF-β_1 and α-SMA is closely related to active proliferation of fibroblasts,extracellular matrix overdeposition and scar contracture of bile duct." @default.
- W2347676543 created "2016-06-24" @default.
- W2347676543 creator A5004907878 @default.
- W2347676543 date "2001-01-01" @default.
- W2347676543 modified "2023-10-03" @default.
- W2347676543 title "An experimental study on mechanism of benign biliary stricture" @default.
- W2347676543 hasPublicationYear "2001" @default.
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