Matches in SemOpenAlex for { <https://semopenalex.org/work/W2347682011> ?p ?o ?g. }
Showing items 1 to 69 of
69
with 100 items per page.
- W2347682011 abstract "To evaluate the efficacy and safety of ramipril in Chinese patients with mild tomoderate essential hypertension, patients with mild to moderate essential hypeftension(sitting diastolic blood pressure in the range of 95~ 114mmHg) were recruited. Group onewas a double-blind, randomized, parallel study. The second group was an open-label study.Ambulatory blood pressure monitoring (ABPM) was performed during a 4-week periodand clinical blood pressure was measured during a 24-week period. After a l-week washoutand 2-week placebo run-in period, the patients were administered ramipril 2.5mg or enalaprillomg for 2 weeks, followed by dose titration to ramipril 5mg or enalapril 20mg for another2 weeks in those patients with blood pressure 90mmHg. At the end of the placebo run-inand 1,2,3,4weeks,the results of clinical blood pressure, heart rate, symptom and physicalcxaminations were recorded. At the end of 4 weeks, no statistical difference was foundbetween the efficacy rates of ramipril (n=61) and enalapril (n=59) (66% vs. 51%, P0.05).SISBP/DBP was decreased by 11.8±11.7/9.4±7.3 mmHg by ramipril and 14.9±12.9 /9.7 ±5.9 mmHg by Enalapril, respectively. Analysis of the ABPM profiles showed thatthe ramipril exerted its antihypertensive effect throughout the 24-h dose-interval withoutaffecting the natural variations. Placebo-corrected trough: peak ratio was 64%. Theantihypertensive effect was maintained from 4 weeks to 24 weeks. Heed rate was unaffectedin any treatment group. The adverse effects in both groups were very mild. The incidenceof cough in the ramipriI group was 6.7%. Ramipril 2.5~5mg once-daily is effective andwell tolerated by Chinese patients with mild to moderate essential hypertension." @default.
- W2347682011 created "2016-06-24" @default.
- W2347682011 creator A5031988329 @default.
- W2347682011 date "2000-01-01" @default.
- W2347682011 modified "2023-09-25" @default.
- W2347682011 title "The Efficacy and Safety of Ramipril in Chinese Patients with Mild to Moderate Essential Hypertension" @default.
- W2347682011 hasPublicationYear "2000" @default.
- W2347682011 type Work @default.
- W2347682011 sameAs 2347682011 @default.
- W2347682011 citedByCount "0" @default.
- W2347682011 crossrefType "journal-article" @default.
- W2347682011 hasAuthorship W2347682011A5031988329 @default.
- W2347682011 hasConcept C126322002 @default.
- W2347682011 hasConcept C126894567 @default.
- W2347682011 hasConcept C142724271 @default.
- W2347682011 hasConcept C149323552 @default.
- W2347682011 hasConcept C197934379 @default.
- W2347682011 hasConcept C204787440 @default.
- W2347682011 hasConcept C27016395 @default.
- W2347682011 hasConcept C27081682 @default.
- W2347682011 hasConcept C2775940317 @default.
- W2347682011 hasConcept C2777097880 @default.
- W2347682011 hasConcept C2777748223 @default.
- W2347682011 hasConcept C2779888176 @default.
- W2347682011 hasConcept C42219234 @default.
- W2347682011 hasConcept C71924100 @default.
- W2347682011 hasConcept C84393581 @default.
- W2347682011 hasConceptScore W2347682011C126322002 @default.
- W2347682011 hasConceptScore W2347682011C126894567 @default.
- W2347682011 hasConceptScore W2347682011C142724271 @default.
- W2347682011 hasConceptScore W2347682011C149323552 @default.
- W2347682011 hasConceptScore W2347682011C197934379 @default.
- W2347682011 hasConceptScore W2347682011C204787440 @default.
- W2347682011 hasConceptScore W2347682011C27016395 @default.
- W2347682011 hasConceptScore W2347682011C27081682 @default.
- W2347682011 hasConceptScore W2347682011C2775940317 @default.
- W2347682011 hasConceptScore W2347682011C2777097880 @default.
- W2347682011 hasConceptScore W2347682011C2777748223 @default.
- W2347682011 hasConceptScore W2347682011C2779888176 @default.
- W2347682011 hasConceptScore W2347682011C42219234 @default.
- W2347682011 hasConceptScore W2347682011C71924100 @default.
- W2347682011 hasConceptScore W2347682011C84393581 @default.
- W2347682011 hasLocation W23476820111 @default.
- W2347682011 hasOpenAccess W2347682011 @default.
- W2347682011 hasPrimaryLocation W23476820111 @default.
- W2347682011 hasRelatedWork W1843339903 @default.
- W2347682011 hasRelatedWork W1979616209 @default.
- W2347682011 hasRelatedWork W2015498975 @default.
- W2347682011 hasRelatedWork W2031375408 @default.
- W2347682011 hasRelatedWork W2034104649 @default.
- W2347682011 hasRelatedWork W2037577465 @default.
- W2347682011 hasRelatedWork W2288951103 @default.
- W2347682011 hasRelatedWork W2352411860 @default.
- W2347682011 hasRelatedWork W2367900000 @default.
- W2347682011 hasRelatedWork W2369557750 @default.
- W2347682011 hasRelatedWork W2385462547 @default.
- W2347682011 hasRelatedWork W2386166731 @default.
- W2347682011 hasRelatedWork W2407902778 @default.
- W2347682011 hasRelatedWork W2413988114 @default.
- W2347682011 hasRelatedWork W2428732664 @default.
- W2347682011 hasRelatedWork W2431160722 @default.
- W2347682011 hasRelatedWork W2461522660 @default.
- W2347682011 hasRelatedWork W3010948704 @default.
- W2347682011 hasRelatedWork W2624282436 @default.
- W2347682011 hasRelatedWork W3012065715 @default.
- W2347682011 isParatext "false" @default.
- W2347682011 isRetracted "false" @default.
- W2347682011 magId "2347682011" @default.
- W2347682011 workType "article" @default.