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- W2347692972 abstract "[Objective]To investigate the association of cytotoxic T lymphocyte-associated antigen-4(CTLA-4) gene polymorphism with idiopathic type 1 diabetes in Chinese Han population.[Methods]The A/G phenotype at position 49 of the CTLA-4 gene was determined by polymerase chain reaction restriction fragment length polymorphism(PCR-RFLP) method in 179 idiopathic type 1 diabetes patients and 290 healthy control subjects of Chinese Han.[Results]The frequencies of the G~(49) allele and GG genotype were significantly higher and AA genotype was significantly lower in idiopathic type 1 diabetes patients than control subjects(P 0.01) . [Conclusion]The polymorphism of CTLA-4 gene A/G~(49) confers susceptibility to idiopathic type 1 diabetes" @default.
- W2347692972 created "2016-06-24" @default.
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- W2347692972 date "2006-01-01" @default.
- W2347692972 modified "2023-09-27" @default.
- W2347692972 title "Association Between CTLA-4 gene A/G~(49) Polymorphism and Idiopathic Type 1 Diabetes" @default.
- W2347692972 hasPublicationYear "2006" @default.
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