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- W2347751574 abstract "Objective:To study the coagulation function at peri-operative period for cyanotic infants with complex congenital heart disease(CCHD)by thromboelastograph(TEG)monitored coagulation changes. Methods:A total of 36 cyanotic CCHD infants were divided into two groups according to hematocrit(HCT)value.High HCT group,n=20,the patients with HCT≥54% and Low HCT group,n=16,HCT54%.The blood samples were collected at anesthesia induction,re-warming at 36℃ time point,after protamine injection and 4 hours after the operation.After the operation,the patient in High HCT group was treated by fibrinogen combined with platelet,Low HCT group was treated with platelet alone.TEG was applied to examine the changes of ①MA,it represents the interaction of platelet and fibrinogen;②MAff,it indicates the contribution of fibrinogen in blood coagulation;③MAp,it shows the effect of platelet in blood coagulation. Results:At anesthesia induction,the MA and MAff were both lower in High HCT group than those in Low HCT group as(44.1±6.8)mm vs.(62.8±6.2)mm and(3.9 ±1.5)mm vs.(14.9±3.5)mm,P0.01 respectively,while Map was similar between two groups,P0.05.After protamine injection the MA and MAff were both lower in High HCT group than those in Low HCT group as(41.7±4.0)mm vs.(46.7± 2.9)mm and(6.0±1.9)mm vs.(10.1 ±1.7)mm,P0.01 respectively,while Map was similar between two groups,P0.05.At 4 hours after the operation,MA,MAff and MAp were all similar between two groups,P0.05 respectively. Conclusion:According to TEG monitoring,cyanotic CCHD infants with high HCT should be treated by fibrinogen combined with platelet after the operation,while the infants with low HCT could be treated with platelet alone." @default.
- W2347751574 created "2016-06-24" @default.
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- W2347751574 date "2012-01-01" @default.
- W2347751574 modified "2023-09-23" @default.
- W2347751574 title "The Application Value of Thromboelastograph at Peri-Operative Period for Cyanotic Infants With Complex Congenital Heart Disease" @default.
- W2347751574 hasPublicationYear "2012" @default.
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