Matches in SemOpenAlex for { <https://semopenalex.org/work/W2347757008> ?p ?o ?g. }
Showing items 1 to 61 of
61
with 100 items per page.
- W2347757008 abstract "Objective To explore the apoptotic effect of trichloroethylene(TCE)on keratinocytes and the relationship with apoptosis inducing factor(AIF). Methods Forty-five BALB/c nude mice were randomly divided into nine groups,which are blank control,solvent control(olive oil),20% TCE group,40% TCE group,80% TCE group,100% TCE group,0.1% ginkgo biloba leaf extract(GbE)group,1% GbE group and 10% GbE group.Mice of the protective groups was pre-treated by skin-smearing with GbE at 1 h before TCE-swearing.All the mice were killed 24 h later after TCE-smearing,the skin was taken under sterile conditions.Apoptotic cells were detected by TUNEL method,and the expression of AIF was detected by immuno-histochemical method. Results The AIF activity and the apoptotic indices in 40% TCE group,80% TCE group and 100% TCE group were significantly differed from blank control group and solvent control group(P 0.01).The higher the concentration of TCE treated,the higher the apoptosis index and the AIF activity;the AIF activities and the apoptosis indices of 1% GbE group and 10% GbE group were significantly differed from 100% TCE group(P 0.05). Conclusions It was suggested that AIF may be involved in the apoptosis of keratinocytes induced by TCE,and GbE has the protective effect on it." @default.
- W2347757008 created "2016-06-24" @default.
- W2347757008 creator A5000113205 @default.
- W2347757008 date "2008-01-01" @default.
- W2347757008 modified "2023-09-23" @default.
- W2347757008 title "Apoptotic mechanism of keratinocyte by trichloroethylene and protective effect of ginkgo biloba leaf extract on it" @default.
- W2347757008 hasPublicationYear "2008" @default.
- W2347757008 type Work @default.
- W2347757008 sameAs 2347757008 @default.
- W2347757008 citedByCount "0" @default.
- W2347757008 crossrefType "journal-article" @default.
- W2347757008 hasAuthorship W2347757008A5000113205 @default.
- W2347757008 hasConcept C178790620 @default.
- W2347757008 hasConcept C185592680 @default.
- W2347757008 hasConcept C190283241 @default.
- W2347757008 hasConcept C196795494 @default.
- W2347757008 hasConcept C2778998842 @default.
- W2347757008 hasConcept C2779404209 @default.
- W2347757008 hasConcept C2780471494 @default.
- W2347757008 hasConcept C55493867 @default.
- W2347757008 hasConcept C556039675 @default.
- W2347757008 hasConcept C71924100 @default.
- W2347757008 hasConcept C98274493 @default.
- W2347757008 hasConceptScore W2347757008C178790620 @default.
- W2347757008 hasConceptScore W2347757008C185592680 @default.
- W2347757008 hasConceptScore W2347757008C190283241 @default.
- W2347757008 hasConceptScore W2347757008C196795494 @default.
- W2347757008 hasConceptScore W2347757008C2778998842 @default.
- W2347757008 hasConceptScore W2347757008C2779404209 @default.
- W2347757008 hasConceptScore W2347757008C2780471494 @default.
- W2347757008 hasConceptScore W2347757008C55493867 @default.
- W2347757008 hasConceptScore W2347757008C556039675 @default.
- W2347757008 hasConceptScore W2347757008C71924100 @default.
- W2347757008 hasConceptScore W2347757008C98274493 @default.
- W2347757008 hasLocation W23477570081 @default.
- W2347757008 hasOpenAccess W2347757008 @default.
- W2347757008 hasPrimaryLocation W23477570081 @default.
- W2347757008 hasRelatedWork W1974235692 @default.
- W2347757008 hasRelatedWork W2022847815 @default.
- W2347757008 hasRelatedWork W2058454184 @default.
- W2347757008 hasRelatedWork W2337394142 @default.
- W2347757008 hasRelatedWork W2347397540 @default.
- W2347757008 hasRelatedWork W2348550913 @default.
- W2347757008 hasRelatedWork W2363344692 @default.
- W2347757008 hasRelatedWork W2365541763 @default.
- W2347757008 hasRelatedWork W2365759493 @default.
- W2347757008 hasRelatedWork W2368351712 @default.
- W2347757008 hasRelatedWork W2374617863 @default.
- W2347757008 hasRelatedWork W2375575395 @default.
- W2347757008 hasRelatedWork W2380989319 @default.
- W2347757008 hasRelatedWork W2381437022 @default.
- W2347757008 hasRelatedWork W2382577789 @default.
- W2347757008 hasRelatedWork W2383374426 @default.
- W2347757008 hasRelatedWork W2385083180 @default.
- W2347757008 hasRelatedWork W2391824483 @default.
- W2347757008 hasRelatedWork W3024545246 @default.
- W2347757008 hasRelatedWork W408230763 @default.
- W2347757008 isParatext "false" @default.
- W2347757008 isRetracted "false" @default.
- W2347757008 magId "2347757008" @default.
- W2347757008 workType "article" @default.