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- W2347766846 abstract "Purpose: To study the morphological method to distinguish aneugens from clastogens. Methods: According to the morphological criteria micronuclei were classified and quantitatively analyzed induced by six reference mutagens (aneugens: colchicine, vincristin; clastogens: cyclophosphamide, mitomycin C, ethyl methane sulfonate, gamma-ray). Results: In comparing with the results by clastogens, the frequency of circle micronuclei by aneugens was significantly increased(P=0.003), ring micronuclei remarkably decreased (P{0.0001}), and crescent micronuclei did not change evidently (P=0.07). The 95% confidence intervals of the mean micronucleus frequencies in class between the two types of mutagens were different very much, of which circle and ring frequences were completely separate. A discriminating function was acquired from the paper data. Conclusion: The frequencies of circle, ring and crescent micronuclei can be as a means to distinguish aneugens and clastogens." @default.
- W2347766846 created "2016-06-24" @default.
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- W2347766846 date "2000-01-01" @default.
- W2347766846 modified "2023-09-26" @default.
- W2347766846 title "STUDY ON THE FREQUENCIES OF MICRONUCLEUS MORPHOLOGICAL CLASS AS A MEANS TO DISTINGUISH ANEUGENS FROM CLASTOGENS" @default.
- W2347766846 hasPublicationYear "2000" @default.
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