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- W2347781545 abstract "A water-soluble chitosan derivative hydroxyethyl chitosan(HECTS) was synthesized by chitosan(CTS) and chlorethanol.HECTS reacted with succinic anhydride and generated N-succinyl-hydroxyethyl chitosan(Suc-HECTS).The best reaction condition was selected by analyzing the experiment conclusions in different conditions to obtain the supreme binding rate of succinic anhydride.The acquired products were characterized by FT-IR.The deacetylation degree,binding rate of succinic anhydride and substitution degree of hydroxyethyl were measured by 1H NMR and elemental analysis.Cytotoxicity of HECTS and Suc-HECTS were evaluated,and the results showed that two materials both had noncytotoxicity.The experimental conclusions offered a theoretical basis for the application of HECTS and Suc-HECTS as biopharmaceutical material and drug carrier." @default.
- W2347781545 created "2016-06-24" @default.
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- W2347781545 date "2011-01-01" @default.
- W2347781545 modified "2023-09-26" @default.
- W2347781545 title "Preparation,characterization and cytotoxicity of hydroxyethyl chitosan and N-succinyl-hydroxyethyl chitosan" @default.
- W2347781545 hasPublicationYear "2011" @default.
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