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- W2347805792 abstract "ObjectiveTo explore the antioxidant role of nimodipine in experimental-epilepsy rats.MethodsFifty Wistar rats were divided into 5 groups: control group,epilepsy group,and 0.1 mg-,0.3 mg-,and 0.5 mg-nimodipine groups.The incubation period,duration,and the onset of epilepsy were observed and SOD,MDA,and GSH-PX of brain tissue were determined in the nimodipine group.The results were compared with those of the PTZ epilepsy group.ResultsThe onset in nimodipine-pretreatment group was characterized by light seizure,prolonged incubation time,short duration and high SOD, low MDA and GSH-PX.There were significantly difference between them(F=10.720-35.831,P0.01).ConclusionAntiepileptic role of nimodipine may be achieved by its antioxidation." @default.
- W2347805792 created "2016-06-24" @default.
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- W2347805792 date "2006-01-01" @default.
- W2347805792 modified "2023-09-25" @default.
- W2347805792 title "ANTIOXIDANT EFFECT OF NIMODIPINE ON RATS WITH EPILEPSY INDUCED BY PENTETRAZOLE" @default.
- W2347805792 hasPublicationYear "2006" @default.
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