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- W2347827219 abstract "Objective To investigate the feasibility of mapping sentinal lymph node(SLN) in vivo and in vitro and clinical significance of sentinel lymph node in rectal cancer.Methods Forty-seven patients treated by surgery for rectum were admitted to this hospital.A subserosal peritumoral injection of methylene blue was given before or after rectal resection.SLNs were harvested and examined by frozen sectioning,HE staining,immunohistochemical staining to identify micrometastasis.Results A total number of 849 lymph nodes were obtained(18.86 per patient).In 97.87%(46/47)of the patients,SLNs were identified with a mean of 1.87.SLN was the only site of metastasis in 8 patients with immunohistochemical staining,but in 2 patients with HE staining.Six patients were upstaged from stage Ⅰ,Ⅱto Ⅲ(AJCC,2002).The upstaging rate from stage Ⅰ,Ⅱto Ⅲ(AJCC,2002)was 23.08%(6/26).Conclusions SLN mapping of rectal cancer can be performed successfully not only in vivo but also ex vivo.Immunohistochemical staining may be helpful for upstaging of rectal cancer." @default.
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- W2347827219 date "2009-01-01" @default.
- W2347827219 modified "2023-09-28" @default.
- W2347827219 title "Clinical significance of sentinal lymph node mapping in rectal cancer surgery" @default.
- W2347827219 hasPublicationYear "2009" @default.
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