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- W2347863485 abstract "[ Objective] To explore the relationship between of nutrients intake and body immunity competence in pre-elderly population.[ Methods] The investigation by a dietary questionnaire was conducted and the immune function as monitored for 3 months. 24-hour dietary record method in 3 days was used. T and B lymphocytes and the subform of T lymphocyte were measured by flow cytometry. Immune nephelometery was used to test IgA,IgG and IgM. IL-2,TNF-α and IFN-γ were determined by ELISA and the phagocytosis activity of neutrophilic granulocytes was tested.[ Results] A positive correlation between the index of IgA and age,and a negative correlation between the percentage of CD3+ lymphocyte and age were shown. Dietary lipid intake was a little more than the RNI. Several micronutrients intakes were in deficiency,especially calcium. From the multiple regression analysis,a positive correlation between the intake of retinol and serum TNF-α content and phagocytosis activity of neutrophilic granulocytes,while a negative correlation between the intake of retinol and CD3+CD4+ lymphocytes were shown. The intake of vitamin C was positively correlated to the percentage of CD3+CD8+ lymphocytes,and negatively correlated to CD3+CD4+/CD3+CD8+. The intake of vitamin E was positively correlated to serum IL-2 content. A positive correlation between the intake of iron and copper and phagocytosis activity of neutrophilic granulocytes were also shown.[ Conclusion] There is some change in immune competence in the pre-elderly population and several nutrients are correlated to immune function. Good nutritional status of people may alleviate immunosenescence." @default.
- W2347863485 created "2016-06-24" @default.
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- W2347863485 date "2006-01-01" @default.
- W2347863485 modified "2023-09-25" @default.
- W2347863485 title "Study on the Relationship between Immune Competence and Nutrients Intake in the Pre-elderly Population" @default.
- W2347863485 hasPublicationYear "2006" @default.
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