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- W2347898181 abstract "Objective To explore the regulation of hypothalamus-pituitary motilin on interdigestive gastric motility.Methods The expression of pituitary motilin was monitored with immunofluorescent histochemical staining in adult SD rats.Changes in serum motilin and gastric migrating motor complex(MMC) were observed in vivo with the multi-lead physiological recording system,following pituitectomy of rats.Results(1) The frequency and amplitude of the contractive gastric MMC both increased following injection of motilin into the hypothalamic paraventricular nuclei(PVN)(P0.05).(2) Two days after pituitectomy,the frequency and amplitude of the contractive gastric MMC both decreased significantly(P0.05).When motilin was injected into the paraventricular nuclei after pituitectomy,the frequency of the gastric MMC increased(P0.05)and the amplitude of MMC elevated obviously(P0.05).(3)Results of immunohistochemical staining indicated that there was expression of immune positive response substances to motilin in the hypothalamus.Conclusion The hypothalamus-pituitary was involved in the regulation of interdigestive gastric motility." @default.
- W2347898181 created "2016-06-24" @default.
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- W2347898181 date "2012-01-01" @default.
- W2347898181 modified "2023-09-24" @default.
- W2347898181 title "Regulation of hypothalamus-pituitary motilin on interdigestive gastric motility" @default.
- W2347898181 hasPublicationYear "2012" @default.
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