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- W2347945504 abstract "OBJECTIVE To investigate the significance of anti-α-Fodrin antibody in the diagnosis and differential diagnosis of Sj觟gren's syndrome.METHODS Serum anti-α-Fodrin IgA and IgG antibodies of patients with primary Sj觟gren's syndrome(pSS,n = 72),secondary Sj觟gren's syndrome(sSS,n = 32),systemic lupus erythematosus(SLE,n = 78),rheumatoid arthritis(RA,n = 120) and normal controls(n = 60) were detected by enzyme-linked immunosorbent assay(ELISA).RESULTS The positive rates of anti-α-Fodrin IgA and IgG antibodies in primary and secondary SS were significantly higher than those in SLE,RA and normal controls(P﹤0.05).The sensitivities of anti-α-Fodrin IgA and IgG antibodies were 55.8% and 44.2%,respectively.The specificities of anti-α-Fodrin IgA and IgG antibodies were 97.5% and 99.0%,respectively.CONCLUSION As a new diagnostic marker for patients with SS,anti-α-Fodrin antibody had high specificity.It is helpful for the diagnosis of SS especially for patients with negative ANA,anti-SSA and anti-SSB antibodies." @default.
- W2347945504 created "2016-06-24" @default.
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- W2347945504 date "2012-01-01" @default.
- W2347945504 modified "2023-09-23" @default.
- W2347945504 title "Significance of anti-α-fodrin antibody in the diagnosis and differential diagnosis for Sjgren's syndrome" @default.
- W2347945504 hasPublicationYear "2012" @default.
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