Matches in SemOpenAlex for { <https://semopenalex.org/work/W2347954629> ?p ?o ?g. }
Showing items 1 to 55 of
55
with 100 items per page.
- W2347954629 abstract "MicroRNAs(miRNAs) regulate the expression of more than 30% genes in animals.CAF1 and POP2 are exoribonucleases that play a key role in miRNA mediated mRNA deadenylation.The expression of CAF1 and POP2 in different tissues of mouse by qRT-PCR is analyzed.The expression of CAF1 is much higher than POP2 in most tissues,with highest expression level in cerebra,cerebel and testis.Through the alignment of protein sequence,it is found that CAF1 and POP2 are highly conserved exonuclease from yeast to human.Yeast encodes only one CAF1/POP2 homologeous.After the emergence of miRNAs,organism evolved two paralogs-CAF1 and POP2.POP2 are less conserved than CAF1 and contain a distinct amino acid sequences at the C-terminus.The results indicate that CAF1 may mainly take part in mRNA deadenylation mediated by miRNA while POP2 may have other regulatory functions." @default.
- W2347954629 created "2016-06-24" @default.
- W2347954629 creator A5068747906 @default.
- W2347954629 date "2010-01-01" @default.
- W2347954629 modified "2023-09-23" @default.
- W2347954629 title "Evolution Analysis of Key Deadenylase in miRNA Mediated mRNA Degradation" @default.
- W2347954629 hasPublicationYear "2010" @default.
- W2347954629 type Work @default.
- W2347954629 sameAs 2347954629 @default.
- W2347954629 citedByCount "0" @default.
- W2347954629 crossrefType "journal-article" @default.
- W2347954629 hasAuthorship W2347954629A5068747906 @default.
- W2347954629 hasConcept C104317684 @default.
- W2347954629 hasConcept C105580179 @default.
- W2347954629 hasConcept C145059251 @default.
- W2347954629 hasConcept C185592680 @default.
- W2347954629 hasConcept C2777576037 @default.
- W2347954629 hasConcept C2779222958 @default.
- W2347954629 hasConcept C55493867 @default.
- W2347954629 hasConcept C86803240 @default.
- W2347954629 hasConcept C95444343 @default.
- W2347954629 hasConceptScore W2347954629C104317684 @default.
- W2347954629 hasConceptScore W2347954629C105580179 @default.
- W2347954629 hasConceptScore W2347954629C145059251 @default.
- W2347954629 hasConceptScore W2347954629C185592680 @default.
- W2347954629 hasConceptScore W2347954629C2777576037 @default.
- W2347954629 hasConceptScore W2347954629C2779222958 @default.
- W2347954629 hasConceptScore W2347954629C55493867 @default.
- W2347954629 hasConceptScore W2347954629C86803240 @default.
- W2347954629 hasConceptScore W2347954629C95444343 @default.
- W2347954629 hasOpenAccess W2347954629 @default.
- W2347954629 hasRelatedWork W1567346019 @default.
- W2347954629 hasRelatedWork W1843014747 @default.
- W2347954629 hasRelatedWork W1871314692 @default.
- W2347954629 hasRelatedWork W1983710378 @default.
- W2347954629 hasRelatedWork W1984194569 @default.
- W2347954629 hasRelatedWork W2006583056 @default.
- W2347954629 hasRelatedWork W2016674854 @default.
- W2347954629 hasRelatedWork W2049868101 @default.
- W2347954629 hasRelatedWork W2056644877 @default.
- W2347954629 hasRelatedWork W2057738635 @default.
- W2347954629 hasRelatedWork W2061841671 @default.
- W2347954629 hasRelatedWork W2068687752 @default.
- W2347954629 hasRelatedWork W2069208087 @default.
- W2347954629 hasRelatedWork W2076746298 @default.
- W2347954629 hasRelatedWork W2080182910 @default.
- W2347954629 hasRelatedWork W2152252110 @default.
- W2347954629 hasRelatedWork W2157811434 @default.
- W2347954629 hasRelatedWork W2364484758 @default.
- W2347954629 hasRelatedWork W2417834442 @default.
- W2347954629 hasRelatedWork W2507906552 @default.
- W2347954629 isParatext "false" @default.
- W2347954629 isRetracted "false" @default.
- W2347954629 magId "2347954629" @default.
- W2347954629 workType "article" @default.