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- W2347963521 abstract "Objective To investigate the clinical significance of T lymphocyte subsets in peripheral blood from patients with Sjogren Syndrome(SS).Methods Lymphocyte subsets were determined in the peripheral blood from SS patients and healthy controls with two-color flow cytometry using various monoclonal antibodies.The relationship between T lymphocyte subsets and disease activity as measured by erythrocyte sedimentation rate(ESR) and serum IgG were analyzed.Results Percentages of CD8+,CD8+ CD28+T lymphocyte subsets and the ratio of CD8+/ CD4+ were significantly decreased in SS patients as compared with controls(P0.05),while percentages of CD4+,CD4+ CD45RA+ and CD4+ CD28+ T lymphocyte subsets did not differ between controls and SS(P0.05).Percentage of CD8+ T lymphocyte subsets and the ratio of CD8+/CD4+ were significantly decreased in patients with active SS.Conclusion Abnormal T lymphocyte subsets were seen in peripheral blood from SS patients and related to the disease activity of SS,which could play an important role in the pathogenesis of SS." @default.
- W2347963521 created "2016-06-24" @default.
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- W2347963521 date "2007-01-01" @default.
- W2347963521 modified "2023-09-26" @default.
- W2347963521 title "Clinical significance of T lymphocyte subsets in peripheral blood from patients with Sj gren syndrome" @default.
- W2347963521 hasPublicationYear "2007" @default.
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