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- W2347992248 abstract "In the present work,we reported the chemiluminescence in phenanthroline-Cu-H 2 O 2 -DNA system and studied the protection of several natural antioxidants on DNA damage. The kinetic curve of chemiluminescence produced in the phen-Cu(Ⅱ)/H 2 O 2 /ascorbate system was immediately recorded with a type BPCL-4 luminescence(manufactured in Institute of Biophysics,China). Depending on the effect on luminescence,the antioxidants studied may be classified into three types which are inhibiting type,delaying type and mixing type,respectively.The results from analysis of molecular structures and quantum mechanical calculations showed that the delay is related to the carbonyls of antioxidant molecules and the level of delaying depend on the net charges on carbonyl carbon,and the inhibition is related to the phenolic hydroxyl and the electron density. There is some law existing in LUMO and HOMO.Above results suggest that this method could not only evaluate the antioxidative effect but also distinguish different types of antioxidants." @default.
- W2347992248 created "2016-06-24" @default.
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- W2347992248 date "1999-01-01" @default.
- W2347992248 modified "2023-09-25" @default.
- W2347992248 title "The Chemiluminescence Analysis of Antioxidants in Vitro" @default.
- W2347992248 hasPublicationYear "1999" @default.
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