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- W2347993496 abstract "Objective:To get more knowledge that helps us to better understand the relationship between serum leptin levels and insulin concentrations, body mass index (BMI), fasting blood glucose (FBG) in type 2 diabetes patients(DM). Methods:The serum leptin levels, insulin concentrations, BMI, FBG were measured in 50 patients with type 2 DM of which 25's BMI≥25(obese group), 25's BMI25(lean group), and 50 nondiabetic people of which 25's BMI≥25(obese group), 25's BMI25(lean group). Data of each person were compared with others and multiple linear regression was adopted to analyze relationships between these indices . Results: The serum leptin levels in obese groups of type 2 DM patients (11.98±3.8)μg/L and nondiabetic people (11.51±3.8)μg/L were higher than those in lean groups of type 2 DM (5.16±2.86)μg/L and nondiabetic people (4 48±2 3)μg/L (P0.001). For both nondiabetic people and type 2 DM patients , the insulin concentrations were higher in obese groups than those in lean groups (P0 01). The leptin levels in obese and lean groups were both positively correlated to BMI (r=0 77, r=0 72, P0 001) and insulin concentrations (r=0 72, r=0 75, P0 001), but not to FBG (r0 19, P0 2). Conclusion: Serum leptin levels are positively correlated with BMI, suggesting that obese patients with type 2 DM are resistant to leptin. The positive correlation between leptin levels and insulin concentrations suggests that there might be insulin resistance in patients with type 2 DM." @default.
- W2347993496 created "2016-06-24" @default.
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- W2347993496 date "2002-01-01" @default.
- W2347993496 modified "2023-09-27" @default.
- W2347993496 title "Relationship between Serum Leptin and Insulin Concentrations , Fasting Blood Glucose in Type 2 Diabetes" @default.
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