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- W2347996886 abstract "Objective: To observe the changes of cognitive function and expression of Cyt-cin in hippocampus of rats with type 1 diabetic mellitus.Methods: Twenty adult SD rats were randomly devided into a control group and an experimental group,10 in each.Type 1 diabetis was induced by one-off injection of streptozotocin(60 mg/kg)in the experimental group.Cognitive function was assessed with the Morris water maze test and the expression of Cyt-cin in hippocampus was detected with the Western blotting method.Results: Compared with the control group,escape latency was prolonged and strategy of platform was scored lower in the experimental group(P0.05);the expression of Cyt-cin in hippocampus was enhanced(P0.05).Conclusion: Type 1 diabetic rats had difficult cognition,which may be related to increase in the expression of Cyt-cin in hippocampus." @default.
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- W2347996886 date "2011-01-01" @default.
- W2347996886 modified "2023-09-24" @default.
- W2347996886 title "Cognitive Function and Expression of Cyt-cin in the Brain of Type 1 Diabetic Rats" @default.
- W2347996886 hasPublicationYear "2011" @default.
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