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- W2348040491 abstract "Objective: To investigate effects of ultrafiltration process on transmittance of active ingredients from Shengmai injection. Method: With transmittance of ginsenosides Rg1,Re,Rb1and schisandrin as indexes,orthogonal test was adopted to investigate effects of temperature,pressure and polysulfone membrane aperture on ultrafiltration process of Shengmai injection. HPLC was adopted to determine contents of index components with mobile phase of acetonitrile( A)-water( B)( 0-30 min,0%-10% A; 30-40 min,10%-23% A; 40-50 min,23% A; 50-85 min,23%-60% A; 85-95 min,60%-100% A) and detection wavelength at 203 nm. Result: The best ultrafiltration process was as follows: temperature45 ℃, pressure 11 psi, polysulfone membrane aperture 50K; Under these conditions,transmittance of ginsenosides Rg1,Re,Rb1and schisandrin were 80. 26%,85. 02%,50. 69%,94. 99%,respectively. Conclusion: Ultrafiltration process had a certain effect on transmittance of active ingredients from Shengmai injection, it could provide experimental basis for improvement of filtration process of Shengmai injection." @default.
- W2348040491 created "2016-06-24" @default.
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- W2348040491 date "2014-01-01" @default.
- W2348040491 modified "2023-09-25" @default.
- W2348040491 title "Effects of Ultrafiltration Process on Transmittance of Active Ingredients from Shengmai Injection" @default.
- W2348040491 hasPublicationYear "2014" @default.
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