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- W2348052246 abstract "OBJECTIVE To investigate the expressions of markers of myoepithelial cells (p75NTR, D2-40 and P63) in fibroadenoma of breast, ductal carcinoma in situ (DCIS) and invasive ductal carcinoma (IDCA). And to make a distinction between the DCIS and IDCA in the same breast organizations and test the expressions of HER-2. METHODS Detected the expression lever of p75NTR, D2-40 and P63 in 68 cases of fibroadenoma of breast, DCIS and IDCA by immunohistochemistry; and detected the expression of HER-2 gene in 28 cases of DCIS and IDCA by FISH. RESULTS The differences in the expression of p75NTR, D2-40 and P63 between the fibroadenoma of breast and DCIS had no statistical significance. But it was meaningful between DCIS and IDCA. Detected the expression of HER-2 gene in 28 cases of DCIS and IDCA at the same time, the concordance rate of HER-2 gene expression in the DCIS and IDCA was 7.14% (2 / 28). CONCLUSION The combination of p75NTR, D2-40 and P63 is ideal marker of myoepithelial cells, which can help us to ensure the accuracy of the HER-2 gene detection." @default.
- W2348052246 created "2016-06-24" @default.
- W2348052246 creator A5007598897 @default.
- W2348052246 date "2013-01-01" @default.
- W2348052246 modified "2023-09-24" @default.
- W2348052246 title "The application of p75~(NTR), D2-40 and P63 in the expression of breast cancer and detection of HER-2 gene" @default.
- W2348052246 hasPublicationYear "2013" @default.
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