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- W2348060725 abstract "Objective:To study the effect of Shiquan Dabu Decoction on MMP-9 gene expression in Lewis lung cancer mice.Methods:The 50 mice were randomly divided into 5 groups:the model group,the Cyclophosphamide group,the low、middle and high dosage groups of Shiquan Dabu Decoction after the cancerometastasis mice model of Lewis lung cancer were established by inoculating tumor cell.The gene expression of MMP-9 in tumour tissues were detected by reverse-transcription polymerase chain reaction(RT-PCR).Results:The tumor metastasis inhibition rate in the middle and high dosage groups of Shiquan Dabu Decoction were 43.20% and 29.59% respectively.Moreover,the contents of MMP-9 genes,compared with model group,were decreased(P0.01).Conclusion:Reducing gene expression of MMP-9 was one of molecular mechanism of Shiquan Dabu Decoction inhibiting lung cancer's metastasis." @default.
- W2348060725 created "2016-06-24" @default.
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- W2348060725 date "2011-01-01" @default.
- W2348060725 modified "2023-09-27" @default.
- W2348060725 title "Effect of Shiquan Dabu Decoction on MMP-9 gene Espression in Lewis Lung Cancer Mice" @default.
- W2348060725 hasPublicationYear "2011" @default.
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