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- W2348061406 abstract "Objective In order to observe the Fangji Huangqi Decoction and modified Fangji Huangqi Decoction on expression of P-cadherin and FSP-1 gene in TGF-β1-induced podocytes.Methods Unified cultured podocytes,then divided into 4 groups after the differentiation and maturation.Podocyte of model group and normal group were incubated in culture medium containing 10% normal rat serum,the model group and intervention group with TGF-β 1 stimulates,intervention group were respectively based on the medium containing 10% Fangji Huangqi decoction,10% modified Fangji HuangqiDecoction drug containing serum of rats with.Using reverse transcription polymerase chain reaction(RT-PCR)technique for the detection of P cadherin,FSP-1 gene expression.Results Compared with normal group,model group,P-cadherin gene expression was significantly reduced,while FSP-1 was no significant difference;Compared with the model group,the intervention group the expression of P cadherin is significantly increased,the normal group,model group,and intervention group had no significant difference in FSP-1 expression.Conclusion Fangji Huangqi Decoction and modified Fangji Huangqi decoctioncan maintain podocyte phenotype molecule expression." @default.
- W2348061406 created "2016-06-24" @default.
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- W2348061406 date "2013-01-01" @default.
- W2348061406 modified "2023-09-25" @default.
- W2348061406 title "Impact of Fangji Huangqi Decoction for the Podocyte Function of Protein Gene Expression" @default.
- W2348061406 hasPublicationYear "2013" @default.
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