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- W2348197289 abstract "Objective: To study the change of hemobilirubin and Cystatin C of hyperbilirubinemia and the investigate value of renal damage.Methods:44 newborns with hyperbilirubinemia were collected in our hospital from October 2009 to October 2010,which were observational members.The ICT is classified as low-grade ICT,220~265μmol/L,middle-grade ICT,265~342μmol/L,high-grade,greater than 342 μmol/L.The contrapositive group includes 40 members without hyperbilirubinemia in our hospital at the same period.All the newborns were exsanguinate 3ml blood from femural vein,tested hepatic function,creatinine,BUN,β2-MG and Cystain C.Test hemobilirubin and Cystain C again when the ICT was fadeaway and deal with statistic methods.Results:There are 21 newborns in low-grade,23 newborns in high-grade,40 newborns in constrapositive group.The figure about total bilirubin and indirect bilirubin has great difference between observational group and contrapositive group(P0.01).There is no significant difference between two groups(P0.05).The Cystatin C and β2-MG of observational group are much higher than contrapositive group.(P0.01,P0.05),which indicates the more serioud the ICT is,the bigger the figure of Cystatin C and β2-MG is,the bigger the renal damage is.The level of total bilirubin,Cystatin C,β2-MG of observational group drops sharply after being treated.The Cystatin C′s dropping level after being treated between observational group and contrapositive group is same(P0.05).The serous Cystatin C,β2-MG has positively relation with TBil.(r=0.71,0.42,P0.01).The figure of BUN,Cr has no relation with TBil.(r=0.24,P0.05) Conclusions: The newborn hyperbilirubinemia maybe bad for kidney,especially the perinatal period newborn.But the damage is reversible and temporal.According to test hemocystain C of newborns with hyperbilirubin,we can find out the kidney injury earlier,prevent using kidney damage drugs and intervene earlier,improve the cure rate." @default.
- W2348197289 created "2016-06-24" @default.
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- W2348197289 date "2012-01-01" @default.
- W2348197289 modified "2023-09-26" @default.
- W2348197289 title "The investigate value of Cystain C study in hyperbilirubinemia renal damage of newborn in perinatal period" @default.
- W2348197289 hasPublicationYear "2012" @default.
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