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- W2348198574 abstract "Objective To investigate the expression of miR-421 in gastric cancer and its effect on cancer cell proliferation. Methods The expression level of miR-421 in gastric cancer tissues and gastric carcinoma cell lines were analyzed by PCR. miR-421 mimics or miR-421 inhibitors were transfected into gastric carcinoma BGC-823 cells. Cell proliferation in transfected BGC-823 cells was detected by CKK-8 kit. Results miR-421 was over-expressed in human gastric cancer cells and several gastric carcinoma cell lines( P 0. 05). The growth of BGC-823 cells was promoted significantly after transfected with miR-421 mimics( P 0. 05),while the proliferation was inhibited after transfected with miR-421 inhibitors( P 0. 05). Conclusion miR-421 is over-expressed in gastric carcinoma cells and miR-421 may promote the proliferation of gastric carcinoma BGC-823 cells." @default.
- W2348198574 created "2016-06-24" @default.
- W2348198574 creator A5074085076 @default.
- W2348198574 date "2014-01-01" @default.
- W2348198574 modified "2023-09-26" @default.
- W2348198574 title "Expression of miR-421 in gastric cancer and its effect on proliferation of BGC-823" @default.
- W2348198574 hasPublicationYear "2014" @default.
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