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- W2348227229 abstract "Objective To investigate the effect of total flavonoids of epimedium(TFE) on the expression of peroxisome proliferator-activated receptor gamma(PPARγ) in hyperlipemia rats. Methods Thirty-five male SD rats were randomly devided into groups of A(high-fat diet,26rats) and B(full diet,9rats).After establishment of rat models,group A was further randomly devided into 3 subgroups of A1(hyperlipemia model,8rats),A2(treated with TFE 100mg/d,9rats) and A3(treated with TFE 200mg/d,9rats).After 4 weeks,the expression level of PPARγ was measured in each group. Results Compared with group B,the levels of TG,TC and LDL-C in group A were significantly increased(P0.01).After treated with TFE,the levels of TG and TC were lower than those in group A1(P0.05),whereas the expression of PPARγ was dramatically elevated(P0.01).Conclusion TFE plays an important role in protecting the function of endothelial cells by promoting the expression of PPARγ in hyperlipemia rats." @default.
- W2348227229 created "2016-06-24" @default.
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- W2348227229 date "2011-01-01" @default.
- W2348227229 modified "2023-09-28" @default.
- W2348227229 title "Effect of total flavonoids of epimedium on the expression of peroxisome proliferator-activated receptor gamma in hyperlipemia rats" @default.
- W2348227229 hasPublicationYear "2011" @default.
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