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- W2348269224 abstract "Objective To explore the benefit of permissive hypercapnia ventilation(PHV)on treat- ment of acute respiratory distress syndrome(ARDS).Methods From March 1996 to December 2005,27 pa- tients were enrolled in this study.ARDS was diagnosed according to the 1994 AECC definition.Twelne pa- tients received PHV by maintaining the PaCO_2 at 45 to 55 mm Hg as treatment group(T),15 patients re- ceived conventional ventilation as controls(C).Variables included ventilation setting,PaO_2/FiO_2 and blood gas,mortality,ventilation duration and incidence of complication.Results(1)At 24 h and 48 h of ventila- tion,levels of peak inspiratory pressure(PIP),positive end-expiratory pressure(PEEP)and mean airway pres- sure(MAP)in T group were significantly lower than these in controls(P0.01).PaO_2/FiO_2(OI),pH and PaO_2 both didn't differ between two groups.PaCO_2 both significantly differed between two groups.(2)Venti- lation time in T group was shortened(8±2 days vs 11±3 days,P0.01)and there was no difference in mortality between the groups(26.5% vs 25%,P=0.34).Five patients in C group developed pneumothorax and none in T group(P0.05).Conclusion Although no improvement in the survival,PHV was associated with reduction in complication and mechanical ventilation duration." @default.
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- W2348269224 date "2007-01-01" @default.
- W2348269224 modified "2023-09-24" @default.
- W2348269224 title "Permissive hypercapnia ventilation in the treatment of respiratory distress syndrome" @default.
- W2348269224 hasPublicationYear "2007" @default.
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