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- W2348291283 abstract "Objective:To explore the effect of endurance training on level of nitric oxide, activity of nitric oxide synthase and expression of nitric oxide synthase in NAFLD ApoE-knockout mice.Method:Twenty four Eight-week ApoE-knockout mice(all males)were dieted western food for 14 weeks, and randomly were divided into two groups, H group and E group.E group was trained on a treadmill for 60 minutes per day, 5 days per week, 0ograde(at 13 m/ min).Every period ended, mice were sacrificed and liver was saved for measuring activities of total NOS, iNOS, cNOS, level of NO and expression of iNOS and eNOS.Results:The activities of total NOS and iNOS increased significantly in E group, while there was no significantly change of cNOS.The level of NO elevated significantly, iNOS and eNOS mRAN expression up-regulated significantly in E group.Conclusion:Endurance training decreased fat drops and increased the activity of iNOS, total NOS and the level of NO, up-regulated the mRNA expressions of iNOS and eNOS in liver.It indicated that the changes of NO, activity of NOS and mRNA expression of iNOS and eNOS play important roles in NAFLD in endurance training mouse model.." @default.
- W2348291283 created "2016-06-24" @default.
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- W2348291283 date "2008-01-01" @default.
- W2348291283 modified "2023-09-25" @default.
- W2348291283 title "The Effect of Endurance Training on Level of NO,Activity of NOS and mRNA Expression of NOS in NAFLD Mice" @default.
- W2348291283 hasPublicationYear "2008" @default.
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