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- W2348465007 abstract "Objective To investigate the effect of compound Kushen injection combined with chemotherapy on the immune function in Non-small cell lung cancer(NSCLC)patient.Methods Totally 59 inoperable NSCLC patients were randomly divided into the treated group(n=29,treated with compound Kushen injection combined with chemotherapy)and the control group(n=30,treated with chemotherapy alone).Chemotherapy of NP protocol was applied to both groups,determined blood route,IgA,IgM,IgG,T cell subsets one day before chemotherapy and one week after chemotherapy from peripheral blood.Results The WBC and lymphocyte transformation rate of control group was(3.2±1.6)×109·L-1 and(9.1±2.4)%respectively after chemotherapy,that of treated group was(5.2±2.6)×109·L-1 and(19.5±2.6)%respectively,higher than the control group(P0.01).The CD4+ and CD8+ positive cell count(36.7±2.1)%and(38.5±1.7)%in treat group,higher than that in control group which were(30.2±1.3)%and(24.6±1.4)%)(P0.01),IgA,IgM,IgG of thymopentin treated group was significantly different compared with control therapy(P0.05).Conclusion Compound Kushen may alleviate toxicology reaction of chemotherapy,raise the white blood cell of patients and enhance cellular immunologic functions in the NSCLC patients." @default.
- W2348465007 created "2016-06-24" @default.
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- W2348465007 date "2013-01-01" @default.
- W2348465007 modified "2023-09-23" @default.
- W2348465007 title "Effect of compound Kushen injection combined with chemotherapy on immune function in non-small cell lung cancer patient" @default.
- W2348465007 hasPublicationYear "2013" @default.
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