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- W2348502056 abstract "The effects of pH 1.85 acetic acid solution treatment on the herring sperm DNA fiber have been studied by Raman spectroscopy. The studies of the Raman data indicated that the protonation of the DNA fiber is obvious. In those studies, evidence was obtained indicating that some of the protonated cytosine-guanine base pairs is a Hoogsteen type base pairs, in which the guanine conformational change enables the hydrogen bonding of N_7 of guanine and N_3 of cytosine. It was also shown that not only purine but also pyrimidine partly fall off from backbones of dsDNA after treatment with acetic acid, and the protonation of pyrimidine might be stronger than that of purine. Meanwhile, the evidence was found for the breaking of hydrogen bonds caused by protonation, depurination and depyrimidination." @default.
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- W2348502056 date "2003-01-01" @default.
- W2348502056 modified "2023-09-23" @default.
- W2348502056 title "Raman Spectral Study of Protonation and Depyrimidination in the Herring Sperm DNA Fiber" @default.
- W2348502056 hasPublicationYear "2003" @default.
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