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- W2348527473 abstract "Objective To establish an animal model of brain damage induced by α radiation.Methods Neonate rats were irradiated with a single injection of 2 μl enriched* 235 uranium( 235 U)into the lateral ventricle of the rat brain on the first day of life(less than 24 hours after birth)at doses of 0,1,5 and 10 μg of* 235 U,respectively.Effects of* 235 U at various doses on their early development and growth were observed.Location of radioactive nucleotide in the brain was traced with autoradiography.Results Radioactive nucleotide could be mainly traced in the cell nucleus and sometimes in the cytoplasm and intercellular space after injected with enriched* 235 U into the brain of neonate rats,forming the basis for developing brain damage and possibly causing reduction of their body weight and brain weight in neonate rats and delay in neurobehavioral development.Conclusions Inner alpha radiation to the brain with enriched uranium could induce developing brain damage in the neonate rats." @default.
- W2348527473 created "2016-06-24" @default.
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- W2348527473 date "2001-01-01" @default.
- W2348527473 modified "2023-09-25" @default.
- W2348527473 title "Studies on damage to the developing brain induced by α-radiation in an animal model" @default.
- W2348527473 hasPublicationYear "2001" @default.
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