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- W2348539013 abstract "[Objective] To explore the expression of tumor necrosis factor-α(TNF-α)and nuclear factor-κB(NF-κB) in the cerebral hematoma peripheral zone after cerebral hemorrhage in patients.[Methods] 10 patients with acute cerebral hemorrhage were studied.The brain tissue surrounded the hematoma was obtained from craniotomy performed after the onset. The brain tissue obtained from two victims in vehicle accidents was used as control.Photomicrography was used to study the histological feature of peri-hematoma tissue with HE staining,and the expression of TNF-α or NF-κB protein was investigated by immunohistochemistry.[Results] TNF-α and NF-κB were detected in all patients of acute cerebral hemorrhage.The expression of TNF-α and NF-κB increased at day 1,peaked at day 3,decreased at day 7,and recovered to normal level at day 14.No or little expression of TNF-α and NF-κB was found in the control group.[Conclusions] The high expression of TNF-α and NF-κB exist in the surrounding tissue of cerebral hematoma after acute cerebral hemorrhage in patients,and leukocytes and lymphocytes infiltration exist in the surrounding tissue of cerebral hematoma." @default.
- W2348539013 created "2016-06-24" @default.
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- W2348539013 date "2007-01-01" @default.
- W2348539013 modified "2023-09-23" @default.
- W2348539013 title "Expression of TNF-α and NF-κB in the surrounding tissue of cerebral haematoma after cerebral hemorrhage" @default.
- W2348539013 hasPublicationYear "2007" @default.
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