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- W2348560986 abstract "OBJECTIVE:To study the dosimetric differences of three dimensional radiotherapy(3D-CRT) and intensity modulated radiotherapy(IMRT) in stereotactic body radiation therapy(SBRT) of early-stage non-small cell lung cancer(NSCLC).METHODS:Twelve patients who received RT with early-stage NSCLC were selected.For every patient 3D-CRT and IMRT plans were designed.The dosimetric parameters of PTV(CI,HI,D1%,D99%),lung,chest wall,heart and spinal-cord Vx,Dmean,Dmax,the total MUs and delivery time were compared.RESULTS: The PTV CI,HI and D1% of 3D-CRT were lower than that of IMRT and with statistical significant difference(P0.05);while the D99% was similar between two plans(P0.05).The differences in V5 to V40 of ipsilateral lung,V5 to V15 of health lung,V5 to V40 of total lung,V5 to V40 and mean dose of chest wall,V20 to V40 and mean dose of heart,maximum dose of spinal cord were no statistically significance between 3D-CRT and IMRT(P0.05).The MUs of 3D-CRT and treatment time were reduced by 53% and 78% compared to IMRT(P0.05).Comparing to the volume of absolute dose,the V60-V75 and V45-V60 of 3D-CRT were slightly larger than that of IMRT,the V20-V45 was smaller than that of IMRT,and the difference was not statistically significant(P 0.05).CONCLUSIONS: There's no significant dosimetry advantage in SBRT of early-stage NSCLC applying IMRT.3D-CRT should be the chief approach for SBRT of NSCLC considering the complex and uncertainties of IMRT." @default.
- W2348560986 created "2016-06-24" @default.
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- W2348560986 date "2013-01-01" @default.
- W2348560986 modified "2023-09-22" @default.
- W2348560986 title "Dosimetric differences between three dimensional radiotherapy and intensity modulated radiotherapy in stereotactic body radiation therapy of non-small cell lung cancer" @default.
- W2348560986 hasPublicationYear "2013" @default.
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