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- W2348573640 abstract "Jatropherol I(JaI), a diterpene separated from Jatropha curcas seed oil was used to (evaluate) its toxicity to 3rd-instar silkworm, Bombys mori L., as well as its effects on midguts tissue and (proteinases) activity of midguts. The results showed that JaI had no contact toxicity but strong stomach (toxicity) to 3rd-instar silkworm. The LC_(50) value were (0.579),(0.220) and (0.158 mg/mL) (respectively) at 48, 72 and 120 h after ingestion of JaI. JaI had a (significant) antifeedant effect to silkworm with AFC_(50) of (0.160) and 0.145 mg/mL, respectively at 24 h and 48 h. A strong inhibition with obvious dose and time dependent effect was observed in JaI on the growth of silkworm. The (inhibitory) effect of JaI increased with time and concentration increased. After silkworm was fed with JaI treated mulberry leaves, (proteinases) activity in midguts reduced with time increased. The activity of proteinases reached the minimum at 48 h after treatment, which was only 32.94%,43.35%,(71.45%) of the control at 0.25,0.125 and (0.062 5 mg/mL,) respectively. Tissue structure of (midguts) in silkworm exposed to JaI was examined by histological method. Damages in epithelial cells and disintegration of fat body were observed. It was (suggested) that damages to insect digestion system induced by JaI might be an important toxicological mechanism of JaI to silkworm." @default.
- W2348573640 created "2016-06-24" @default.
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- W2348573640 date "2005-01-01" @default.
- W2348573640 modified "2023-09-25" @default.
- W2348573640 title "Toxicity and Mechanism of Jatropherol I to Silkworm, Bombys mori L." @default.
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