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- W2348764388 abstract "Objective To study the effects of Avastin combined with peripheral retinal coagulation for advanced neovascular glaucoma retrospectively.Methods A total of 73 neovascular glaucoma patients(73 eyes) were selected in our hospital from May 2006 to December 2010,and divided randomly into group A and B.In group A(45 cases,45 eyes),0.05 mL Avastin(1.25 mg) were injected and peripheral retinal coagulation were performed.In group B(28 cases,28 eyes),only peripheral retinal coagulation were carried out.The follow-up time was 6 months,and the preoperative and postoperative iris neovascularization,visual acuity,intraocular pressure and corneal endothelial cell counting were observed and compared.Results The iris neovascularization at postoperative 1 day in group A obviously reduced and thinned,which disappeared in 17 patients at postoperative 3 days,the angle neovascularization was atrophied,and disappeared in all patients 2 weeks later,however these in group B were obviously seen at postoperative 3 days and 2 weeks,and disappeared 1 month later.The intraocular pressure in group A was controlled better at each postoperative time point,which at postoperative 2 weeks,1 month,3 months and 6 months were 18.24 mmHg(1 kPa=7.5 mmHg),17.48 mmHg,17.35 mmHg and 16.87 mmHg,respectively,obviously lower than those in group B(27.07 mmHg,21.23mmHg,19.36 mmHg and 18.39 mmHg).The corneal endothelial cell counting in group A at postoperative 2 weeks,1 month,3 months and 6 months were 1527.36 mm-2,1548.25 mm-2,1502.34 mm-2 and 1532.45 mm-2,respectively,obviously more than those in group B(1432.54 mm-2,1354.67 mm-2,1389.21 mm-2 and 1364.57 mm-2).Conclusion Intraocular injection Avastin can relieve the pain of advanced neovascular glaucoma,accelerate the iris neovascularization disappear,decrease intraocular pressure and preserve the corneal endothelial cell.Intraocular injection avastin combined with peripheral coagulation can be used as an effective treatment for advanced neovascular glaucoma." @default.
- W2348764388 created "2016-06-24" @default.
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- W2348764388 date "2012-01-01" @default.
- W2348764388 modified "2023-09-25" @default.
- W2348764388 title "Avastin combined with peripheral retinal coagulation for advanced neovascular glaucoma" @default.
- W2348764388 hasPublicationYear "2012" @default.
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