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- W2348773604 abstract "AIM:To evaluate the antibacterial activity of balofloxacin against urinary tract pathogens in vitro.METHODS:Two hundred and forty-nine bacterial tribes were collected from the urine of urinary tract infection patients,including 90 gram-positive bacteria (30 Staphylococcus aureus,27 Staphylococcus epidermidis,18 Enterococcus faecalis,15 Streptococcusβhaemolyticus) and 159 gram-negative bacteria (84 Escherichia coli,20 Klebsiella pneumoniae,25 Enterobacter spp,15 Proteus mirabilis,15 Pseudomonas aeruginosa).The minimum inhibitory concentration (MIC) of balofloxacin and levofloxacin against 249 pathogens of urinary tract infections was determined by agar dilution method.RESULTS:MIC_(90) of balofloxacin (2～8 mg·L~(-1)) was 1/4～1/2 or equal to that of levofloxacin (2～16 mg·L~(-1)) in antagonizing gram-positive bacteria.MIC_(90) of balofloxacin (4～32 mg·L~(-1)) was 2～4 times or equal to that of levofloxacin (2～16 mg·L~(-1)) in treating gram-negative bacteria.CONCLUSION:Balofloxacin possesses antibacterial activity against gram- positive and gram-negative bacteria.Balofloxacin is more powerful than or equal to that of levofloxacin in treating gram-positive bacteria,but less than or equal to that of levofloxacin for gram-negative bacteria." @default.
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- W2348773604 date "2007-01-01" @default.
- W2348773604 modified "2023-09-23" @default.
- W2348773604 title "Antibacterial activity of balofloxacin against urinary tract pathogens in vitro" @default.
- W2348773604 hasPublicationYear "2007" @default.
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