Matches in SemOpenAlex for { <https://semopenalex.org/work/W2348810139> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W2348810139 abstract "Objective To explore the effect and significance of leptin on the expression of p-ERK1/2 and VEGF in A549 cells.Methods A549 cell line was treated with different concentration of letpin for 24,48 or 72 hours,respectively,and then cellular proliferation was evaluated by MTT method.VEGF expression in tumor cells was detected by immuno-histochemical method,Western blot analysis was used to detect both p-ERK1/2 and VEGF expressions.Results MTT assay showed that Leptin stimulated the proliferation of A549 cells in a does and time-dependent manner in vitro(P0.05).The expression of VEGF was upregulated significantly in A549 cells treated by 80ng/ml or 160ng/ml Leptin(P0.05).Western blot showed that the protein expression of VEGF was significantly increased in a Leptin dose-dependent way.There was a positive correlation between p-ERK1/2and VEGF(r=0.694,P0.05).Conclusion Leptin stimulated proliferation of A549 cells and up-regulated VEGF protein expression partly through ERK1/2 pathway." @default.
- W2348810139 created "2016-06-24" @default.
- W2348810139 creator A5062632577 @default.
- W2348810139 date "2010-01-01" @default.
- W2348810139 modified "2023-09-23" @default.
- W2348810139 title "Effects of Leptin on Cell Proliferation and p-ERK1/2,VEGF Expression in Human Lung Adenocarcinoma Cell Line A549" @default.
- W2348810139 hasPublicationYear "2010" @default.
- W2348810139 type Work @default.
- W2348810139 sameAs 2348810139 @default.
- W2348810139 citedByCount "0" @default.
- W2348810139 crossrefType "journal-article" @default.
- W2348810139 hasAuthorship W2348810139A5062632577 @default.
- W2348810139 hasConcept C104317684 @default.
- W2348810139 hasConcept C126322002 @default.
- W2348810139 hasConcept C127561419 @default.
- W2348810139 hasConcept C134018914 @default.
- W2348810139 hasConcept C1491633281 @default.
- W2348810139 hasConcept C153911025 @default.
- W2348810139 hasConcept C167734588 @default.
- W2348810139 hasConcept C185592680 @default.
- W2348810139 hasConcept C2776415932 @default.
- W2348810139 hasConcept C2777025900 @default.
- W2348810139 hasConcept C2780613262 @default.
- W2348810139 hasConcept C2780783641 @default.
- W2348810139 hasConcept C502942594 @default.
- W2348810139 hasConcept C511355011 @default.
- W2348810139 hasConcept C54355233 @default.
- W2348810139 hasConcept C55493867 @default.
- W2348810139 hasConcept C62112901 @default.
- W2348810139 hasConcept C71924100 @default.
- W2348810139 hasConcept C81729549 @default.
- W2348810139 hasConcept C81885089 @default.
- W2348810139 hasConcept C86803240 @default.
- W2348810139 hasConceptScore W2348810139C104317684 @default.
- W2348810139 hasConceptScore W2348810139C126322002 @default.
- W2348810139 hasConceptScore W2348810139C127561419 @default.
- W2348810139 hasConceptScore W2348810139C134018914 @default.
- W2348810139 hasConceptScore W2348810139C1491633281 @default.
- W2348810139 hasConceptScore W2348810139C153911025 @default.
- W2348810139 hasConceptScore W2348810139C167734588 @default.
- W2348810139 hasConceptScore W2348810139C185592680 @default.
- W2348810139 hasConceptScore W2348810139C2776415932 @default.
- W2348810139 hasConceptScore W2348810139C2777025900 @default.
- W2348810139 hasConceptScore W2348810139C2780613262 @default.
- W2348810139 hasConceptScore W2348810139C2780783641 @default.
- W2348810139 hasConceptScore W2348810139C502942594 @default.
- W2348810139 hasConceptScore W2348810139C511355011 @default.
- W2348810139 hasConceptScore W2348810139C54355233 @default.
- W2348810139 hasConceptScore W2348810139C55493867 @default.
- W2348810139 hasConceptScore W2348810139C62112901 @default.
- W2348810139 hasConceptScore W2348810139C71924100 @default.
- W2348810139 hasConceptScore W2348810139C81729549 @default.
- W2348810139 hasConceptScore W2348810139C81885089 @default.
- W2348810139 hasConceptScore W2348810139C86803240 @default.
- W2348810139 hasLocation W23488101391 @default.
- W2348810139 hasOpenAccess W2348810139 @default.
- W2348810139 hasPrimaryLocation W23488101391 @default.
- W2348810139 hasRelatedWork W2046202911 @default.
- W2348810139 hasRelatedWork W2057918209 @default.
- W2348810139 hasRelatedWork W2348698990 @default.
- W2348810139 hasRelatedWork W2358127254 @default.
- W2348810139 hasRelatedWork W2368878072 @default.
- W2348810139 hasRelatedWork W2370483786 @default.
- W2348810139 hasRelatedWork W2370493841 @default.
- W2348810139 hasRelatedWork W2371701716 @default.
- W2348810139 hasRelatedWork W2372061774 @default.
- W2348810139 hasRelatedWork W2376205438 @default.
- W2348810139 hasRelatedWork W2382214071 @default.
- W2348810139 hasRelatedWork W2383775763 @default.
- W2348810139 hasRelatedWork W2386248903 @default.
- W2348810139 hasRelatedWork W2390801946 @default.
- W2348810139 hasRelatedWork W2392896395 @default.
- W2348810139 hasRelatedWork W2393757994 @default.
- W2348810139 hasRelatedWork W2394078161 @default.
- W2348810139 hasRelatedWork W3028926205 @default.
- W2348810139 hasRelatedWork W3032390414 @default.
- W2348810139 hasRelatedWork W3185801752 @default.
- W2348810139 isParatext "false" @default.
- W2348810139 isRetracted "false" @default.
- W2348810139 magId "2348810139" @default.
- W2348810139 workType "article" @default.