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- W2348828885 abstract "Objective To analyze the expression difference of human platelet antigen(HPA)1-17bw gene between Yao and Zhuang nationality in Guangxi.Methods Genotyping of HPA 1-17bw system of 100cases of Yao nationality and 100cases of Zhuang nationality were conducted by using PCR-SSP,and genotype and gene frequency were calculated.Results The alleles a was the common genotype of HPA 1-17bw gene in Zhuang and Yao nationality of Guangxi.H-W population genetic equilibrium test indicated that,in Yao nationality,most gene polymorphisms of HPA 1-17bw gene,excepting HPA1,2and 6gene polymorphisms,were conformable to H-W population genetic equilibrium law(P0.05),and in Zhuang nationality,all HPA system were conformable to H-W rule(P0.05).Among all HPA system,the mismatch rates of HPA3and HPA15were the highest,more than 30%,between Yao and Zhuang nationality.Comparison of gene frequencies between the two groups indicated that the gene polymorphisms of HPA3and HPA15in Yao nationality were lower than Zhuang nationality(χ2=12.242,P=0.002;χ2=6.209,P= 0.045).Conclusion There could be significant ethnic difference of HPA gene polymorphism between Zhuang and Yao nationality in Guangxi.The distribution of HPA3and HPA15gene frequency could be polymorphous,and should be paid more attention in matched platelet transfusion in clinic." @default.
- W2348828885 created "2016-06-24" @default.
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- W2348828885 date "2013-01-01" @default.
- W2348828885 modified "2023-09-28" @default.
- W2348828885 title "Human platelet antigen gene polymorphism analysis in Yao and Zhuang nationality in Guangxi" @default.
- W2348828885 hasPublicationYear "2013" @default.
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