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- W2348918478 abstract "Objective To investigate the effects of decoction of yiqiwenyanghuoxue on Ang Ⅱ and aldosterone(ALD) in rats with early heart failure.Methods Model rats with chronic heart failure(CHF)were injected with Adriamycin and treated by decoction of yiqiwenyanghuoxue,then AngⅡ and ALD levels were detected by radioimmunity.PPARγ mRNA were detected by RT-PCR and protein by Western-blot.Results Compared to the control group,Ang Ⅱ and ALD levels were significantly higher,but PPARγ at mRNA and protein levels were significantly lower in CHF groups.Yiqiwenyanghuoxue decoction could improve the above changes.Conclusions AngⅡ,ALD can be the predictors in early heart failure.Decoction of yiqiwenyanghuoxue can prevent myocardial remodeling and improve heart function through PPARγ regulating AngⅡand ALD levels." @default.
- W2348918478 created "2016-06-24" @default.
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- W2348918478 date "2011-01-01" @default.
- W2348918478 modified "2023-09-25" @default.
- W2348918478 title "Effects of decoction of yiqiwenyanghuoxue on Ang II and ALD in rats with early heart failure" @default.
- W2348918478 hasPublicationYear "2011" @default.
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