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- W2348975767 abstract "Ciguatoxin was a kind of marine toxin exists in coral fish. A trace residual might lead to ciguatera poisoning. In order to build an immunochromatography assay method,it was necessary to synthesize artificial antigen of ciguatoxin firstly. Monensin,an analogue of ciguatoxin,was reconstructed to succinyl monensin through the reaction between succinic anhydride and monensin,and then coupled to bovine serum albumin(BSA)and ovalbumin(OVA)by mixed acid anhydride method to synthesize the artificial antigen MON-HS-BSA and MON-HS-OVA. The antibodies against ciguatoxin were raised in serum of MON-HS-BSA immunized BalB/c mice by indirect competitive ELISA. The above results showed that the artificial antigen of ciguatoxin was synthesized successfully and it could be used to develop monoclonal antibodies against ciguatoxin in the future." @default.
- W2348975767 created "2016-06-24" @default.
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- W2348975767 date "2011-01-01" @default.
- W2348975767 modified "2023-09-23" @default.
- W2348975767 title "Synthesis and identification of artificial antigen of ciguatoxin" @default.
- W2348975767 hasPublicationYear "2011" @default.
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