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- W2348986318 abstract "Objective:To evaluate the effect of early administration of simvastatin at different-dose on the serum C-reactive protein(CRP),fibrin degradation product(FDP)and blood-lipid in the patients with acute coronary syndrome(ACS).Method:A total of 120 patients with ACS were divided into three groups.The patients in group A(n=40) received simvastatin(40mg/day);patients in group B(n=40) received simvastatin(20mg/day)and the group C was the control group(n=40).Patients in group A and B were treated with simvastatin within 24-48 hours after hospitalization.The levels of the high sensitivity CRP(hs-CRP),FDP and the blood-lipid were measured at baseline and after 8 weeks of therapy.Results: After 8weeks of therapy,simvastatin at different-doses can not only decrease the serum level of blood-lipid,but also decrease the serum level of hs-CRP and FDP.The higher dose,the more effective.Conclusions:Early treatment with simvastatin can inhibit inflammation and blood coagulative reation obviously,and the effect is dose-dependent." @default.
- W2348986318 created "2016-06-24" @default.
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- W2348986318 date "2010-01-01" @default.
- W2348986318 modified "2023-09-25" @default.
- W2348986318 title "Effect of simvastatin on acute coronary syndrome" @default.
- W2348986318 hasPublicationYear "2010" @default.
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