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- W2349202934 abstract "Objective To observe the effect of Mycobacterium vaccae preparation on the production of influenza-specific Ig. Methods Immunize BALB / c mice i.m. by influenza vaccine combined with various dosages (11. 25, 22. 5 and 45. 0 μg) of M. vaccae preparation respectively, or by 22. 5 μg of M. vaccae preparation alone, and determine the specific IgM, IgG, IgG1, IgG2a and IgA levels against influenza virus, as well as the time when the Ig appear, in sera. Results The specific IgG and IgG2a levels in sera of mice immunized by influenza vaccine combined with 3 dosages of M. vaccae preparation were significantly higher than those by influenza vaccine alone 4 d, while showed no significant difference 13 d after immunization. No significant difference was observed in specific IgG, IgG1, IgG2a and IgM levels of mice immunized by influenza vaccine combined with various dosages of M. vaccae preparation. The IgA level in sera of mice 10 d after immunization by influenza vaccine combined with M. vaccae increased significantly. However, M. vaccae preparation showed no significant effect on production of specific IgM and IgG1. Conclusion M. vaccae, both inoculated alone or combined with influenza vaccine, promoted the production of specific IgG, IgG2a and IgA against influenza virus." @default.
- W2349202934 created "2016-06-24" @default.
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- W2349202934 date "2008-01-01" @default.
- W2349202934 modified "2023-09-24" @default.
- W2349202934 title "Effect of Mycobacterium vaccae Preparation on Production of Influenza-specific Ig" @default.
- W2349202934 hasPublicationYear "2008" @default.
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