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- W2349231698 abstract "Objective :To evaluate the effects of radiotherapy by field-in-field technique for high grade brain glioma. Method:Twenty eight patients with high grade (Ⅲ-Ⅳ) brain glioma after operation were randomized into two groups (trial and control group). All patients were confirmed by pathology and CT or MR scan. Thirteen cases of (trial group , TG) were treated by field-in-field technique which was delivered by 1.8 Gy per fraction and 5 fractions a week in whole brain field with total doses of 45 Gy in five weeks and 1.5 Gy per fraction and 2 fractions a week in local field with total doses of 15 Gy in the corresponding period, with an interval of 6 hours from whole brain irradiation. Fifteen patients of (control group , CG ) were treated by routine irradiation which was delivered by 2.0 Gy per fraction and S fractions a week in whole brain field with total doses of 40 Gy in four weeks, and 2.0 Gy per fraction and 5 fractions a week in local field with total doses of 20 Gy in two weeks sequentially. Results:The 1-,2- and 3-year survival rates were 69.2%, 53.9%, 35.9% in TG and 60%, 26.7%, 20% in CG respectively. But P value was 0.1197 in the Log-rank test. The medial survival spans were 26 and 17 months. Conclu-sion :The field-in-field technique for high grade brain glioma may increase the 1-, 2- and 3-year survival rates. The improvement of 2-year survival rate is higher than that of 1 - or 3-year. This technique may increase the local radiobiological effect and defer the tumor recurrence" @default.
- W2349231698 created "2016-06-24" @default.
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- W2349231698 date "2007-01-01" @default.
- W2349231698 modified "2023-09-27" @default.
- W2349231698 title "Clinical study on postoperative radiotherapy by field-in-field technique for high-grade brain glioma" @default.
- W2349231698 hasPublicationYear "2007" @default.
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