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- W2349254081 abstract "Objective To identify secreted proteins of non-small cell lung cancer cell line A549 using proteomic approach to detect potential early diagnostic biomarkers of lung cancer. Methods Proteins in the culture supernatant of A549 cells was recovered and subsequently proteomic analysis was performed. Specific protein spots in A549 were identified by peptide mass fingerprints using mass spectrometry and database search. Results 17 secreted proteins spots were identified, which include Peptidyl-prolyl cis-trans isomerase A (PPIA), manganese superoxide dismutase (MnSOD), Peroxiredoxin 1 (PDX1), phosphatidylethanolamine binding protein (PEBP), glutathione S-transferase P (GSTP1-1), glucose-dependent insulinotropic protein receptor(GIPR), Ubiquitin carboxyl-terminal hydrolase isozyme L1 (PGP9.5), Alpha enolase (ENO1), Sequence 299 from Patent WO0222660, Dihydrodiol dehydrogenase 2(DDH), Phosphoglycerate mutase 1 (PGAM1) and Galectin-1. Conclusions Identification of secreted proteins of lung cancer cell is of potential importance for the detection of early diagnostic biomarkers." @default.
- W2349254081 created "2016-06-24" @default.
- W2349254081 creator A5065052053 @default.
- W2349254081 date "2005-01-01" @default.
- W2349254081 modified "2023-09-25" @default.
- W2349254081 title "Proteomics analysis of secreted proteins of human non-small cell lung cancer cell" @default.
- W2349254081 hasPublicationYear "2005" @default.
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