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- W2349274024 abstract "AIM To produce the vaccine, we isolated a strain of canine parainfluenza attenuated virus. METHODS According to the cellular adsorptive and cultural properties of the canine parainfluenza virus, we isolated the virus named CPIV XN 4,by heterovirus anti serum blocking test. We alsoidentified its morphological and biological characteristics. RESULTS The titer of the virus was 10 -6 TCID 50 . There could be seen the typical canine parainfluenza virus particles under the electron microscope. The antibody molecules had been absorbed in the surface of the virus particle, which was observed under the immuno electron microscope. The neutralized antibody titer was 149.62; CPIV XN 4 had a cross neutralized reaction with the international standard strain. There were no deaths 15 days after incobulation in health infant dogs. The attack results showed that two dogs of the control group had nerve symptoms on the 9th day and died 14 days later. No dogs showed any clinical symptoms in the experiment group. CONCLUSION CPIV XN 4 could be a candidate for vaccine strain." @default.
- W2349274024 created "2016-06-24" @default.
- W2349274024 creator A5042655948 @default.
- W2349274024 date "2000-01-01" @default.
- W2349274024 modified "2023-09-23" @default.
- W2349274024 title "Isolation and identification of canine parainfluenza attenuated vaccine strain" @default.
- W2349274024 hasPublicationYear "2000" @default.
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