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- W2349278326 abstract "Objective To study the growth of human basic fibroblast growth factor(hbFGF) gene-modified gingival fibroblasts(GFs) implanted on the acellular dermal matrix(ADM) and provide evidence for gene therapy combined with tissue engineering for the regeneration of periodontal tissue defect.Methods hbFGF gene-transfected GFs were implanted onto ADM.The formation of cell-scaffold composition was observed by fluorescence microscopy,confocal laser scanning microscopy,transmission electron microscopy,hematoxylin and eosin stain.Results The transfected cells grew well on the ADM.Cell attachment and spreading were observed 24 h after implantation.Transmission electron microscopy showed that cells grew well and closely integrated with the scaffold materials.Conclusion hbFGF gene-modified GFs-ADM compound can be used in the periodontal tissue engineering." @default.
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- W2349278326 date "2010-01-01" @default.
- W2349278326 modified "2023-09-23" @default.
- W2349278326 title "Construction of Acellular Dermal Matrix Compounded with hbFGF Gene-Modified Gingival Fibroblasts" @default.
- W2349278326 hasPublicationYear "2010" @default.
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