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- W2349287382 abstract "Objective To detect the relationship of estrogen recptor(ER) expression with microvessel density(MVD) of hepatic metastasis ,primary focus and para-carcinoma tissue of colorectal cancer(CRC). Method 32 cases of CRC with hepatic metastasis were selected as experimental group,33 cases of CRC without organic metastasis as control group. The estrogen recptor expression and microvessel density (MVD) of hepatic metastasis ,primary focus and para-carcinoma tissue of CRC were determined by immunohistochemical staining. Result The expression of ER decreased as the tissue maliganancy increased,the positive rates of ER expression in the normal intestinal mucosa, local focus and hepatic metastasis of experimental group were 23/32,14/32,5/32 respectively, but were 21/33 and 13/33 in the normal intestinal mucosa, primary focus of the control group respectively . The MVD values in the normal intestinal mucosa, local focus and hepatic metastasis of experimental group were 43.19±41.17,68.53±24.26, 29.53±9.27 respectively, but were 51.32±21.82 and 62.98±25.71 in the normal intestinal mucosa, primary focus of the control group respectively. Conclusion The expression of ER, as a protective factor against CRC and its hepatic metastasis, has negative correlation with MVD in primary focus." @default.
- W2349287382 created "2016-06-24" @default.
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- W2349287382 date "2008-01-01" @default.
- W2349287382 modified "2023-09-25" @default.
- W2349287382 title "The Relationship of Estrogen Receptor with Microvessel Density of Human Colonal Rectal Cancer" @default.
- W2349287382 hasPublicationYear "2008" @default.
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