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- W2349291254 abstract "Objective To analyze the clinical features of serum markers and hepatic pathology of HBeAg-negative chronic hepatitis(CHB) patients. Methods 125 cases of HBeAg-negative CHB patients and 125 cases of HBeAg-positive CHB patients were analyzed retrospectively. The serum markers(HBV-DNA and ALT), and pathologic stages of hepatic inflammation activity were observed and compared. Results 1The overall HBV-DNA load and ALT level of HBeAg-positive CHB patients were significantly higher than those of HBeAg-negative CHB patients(both P 0.05). 2 When the HBV-DNA load ≥ 105IU/m L, the ratio of HBeAg-positive CHB was 80.8%(101/125), significantly higher than 64.8%(81/125) of HBeAg-negative CHB(P 0.05). When the ALT level ≥ 80 U/m L, the ratio of HBeAg-positive CHB was 76.8%(96/125), significantly higher than 56.8%(71/125) of HBeAg-negative CHB(P 0.05). Conclusions The serum markers can reflect the hepatic inflammation activity and fibrosis stage of HBeAg-negative CHB patients. HBV-DNA ≥ 105IU/m L maybe a critical value to evaluate if the antiviral therapy should be performed for HBeAg-negative CHB patients." @default.
- W2349291254 created "2016-06-24" @default.
- W2349291254 creator A5066077021 @default.
- W2349291254 date "2015-01-01" @default.
- W2349291254 modified "2023-09-28" @default.
- W2349291254 title "Clinical Analysis Between Serum Markers and Hepatic Pathology of HBeAg-Negative Chronic Hepatitis B" @default.
- W2349291254 hasPublicationYear "2015" @default.
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