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- W2349316875 abstract "Objective To study the gastrointestinal motility changes and mechanisms of rats after orthotopic liver transplantation. Methods Forty rats were randomly divided into 3 groups of orthotopic liver transplantation group (A) (10 pair rats),total hepatic vascular exclusion group (B) and control group (C) with 10 rats each.Orthotopic liver transplantation was performed by means of modified double-cuff method in group A. The group B was operated in accordance with the operating procedure of the receptor of group A,and hold the times of anhepatic phase as same as group A. The rats in group C experienced abdomen opening only.One hour after the operation,the charcoal transit rate in the small intestine,the content of the endotoxin in plasma,the content of Ca2+-ATPase and MDA in the intestine were measured. Results Compared with other groups,the intestine propulsion rate was the lowest,the content of the endotoxin in plasma was the highest,the content of Ca2+-ATPase in the intestine was the lowest and the MDA was the highest in group A.Conclusion In the early phase of post orthotopic liver transplantation,the gastrointestinal motility significantly depressed,which may be related to the intestine energy metabolism disorder,ischemia-reperfusion injury,enterogenous endotoxin translocation and other factors." @default.
- W2349316875 created "2016-06-24" @default.
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- W2349316875 date "2008-01-01" @default.
- W2349316875 modified "2023-09-24" @default.
- W2349316875 title "The changes and mechanisms of gastrointestinal motility in rats after orthotopic liver transplantation" @default.
- W2349316875 hasPublicationYear "2008" @default.
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