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- W2349348233 abstract "Objective To observe the relationship between Hepatic injury due to antituberculosis drugs and infection with hepatitis B virus (HBV) in patients with tuberculosis.Methods Tuberculosis patients with positive results in detection of HBV carriers or those at recovered were recruited in Experimental Group A;The HBV patients and HBV carriers or those at rehabilitating stage were recruited as Experimental Group B;Those with negative results in detection of HBV mark were recruited as controls.The prevalent rates of hepatic injury due to antituberculosis drugs,the time of injury occurred and the increase of ALT,AST and TBL values were observed during the study.Results The prevalent rate of liver damage due to antituberculosis was statistically different in the Experimental Groups as compared with the control group(μ=2.619,P0.01).The time of injury occurred in the Experimental Groups A and B was late than that of Controls and no differences in the increase of ALT,AST and TBL values were observed.Conclusion The prevalent rate liver damage due to antituberculosis drugs in tuberculsosis patients complicated with HBV infection was high but the time of damage occurred was late.Thus Observation should be made during the whole process of treatment of the patients in order to reduce,as much as possible,the injury to the liver." @default.
- W2349348233 created "2016-06-24" @default.
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- W2349348233 date "2003-01-01" @default.
- W2349348233 modified "2023-09-25" @default.
- W2349348233 title "Hepatic injury due to antituberculosis drug and infection with hepatitis B virus" @default.
- W2349348233 hasPublicationYear "2003" @default.
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