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- W2349380986 abstract "Objective To study the protective effect of prostaglandin E1 (PGE1) on the liver in orthotopic liver transplantation rats. Methods PGE1 was infused intravenously during orthotopic liver transplantation in recipient rats. Sham operated and normal saline groups served as control groups. One week survival rate and ultrastructure pathological changes in liver were observed. Results The survival rate in the PGE1 treated group was obviously increased as compared with that in the control group. Electron microscopic examination revealed a dramatic elevation of hepatocellular lysosome number in the control groups, and bleb and rupture of lysosome membrane were also observed in the PGE1 trated group. Conclusions PGE1 treatment during recipient operation could increase one week survival rate, which might be related with its stabilizing effect on lysosome membrane." @default.
- W2349380986 created "2016-06-24" @default.
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- W2349380986 date "2001-01-01" @default.
- W2349380986 modified "2023-09-26" @default.
- W2349380986 title "Experiment study on the relationship between the protective effect of prostaglandin E1 and the lysosome in orthotopic liver transplantation in rats" @default.
- W2349380986 hasPublicationYear "2001" @default.
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