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- W2349396071 abstract "Objective To investigate the correlation between serum visfatin and fasting serum insulin(FINS),fasting plasma glucose(FPG),TNF-α,and insulin resistance(HOMA-IR)in pregnant women with different glucose tolerance.Methods According to the results of oral glucose tolerance test,pregnant women who underwent antenatal examination were stratified into three groups:GDM group(n=45),GIGT group(n=70),and NGT group(n=97).The concentrations of FPG,FINS,visfatin and TNF-αwere measured,and then HOMA-IR was calculated.The relationship among these indexes were analyzed.Results The GDM group showed higher levels of FBG,HOMA-IR,FINS,visfatin and TNF-αas compared with GDM and NGT group(P 0.01).The levels of HOMA-IR,FINS and visfatin in GIGT group were higher than those in NGT group(P0.01or P0.05),but there were no significant differences in FPG and TNF-αlevels between the two groups(P0.05).The levels of visfatin in GDM and GIGT group were positively correlated with FBG,HOMA-IR,FINS and TNF-α.Multiple logistic regression analysis revealed HOMA-IR as an independent association factor for plasma visfatin levels.Conclusion Visfatin may play a role in gestational diabetes mellitus,and the increase of visfatin may be related to HOMA-IR." @default.
- W2349396071 created "2016-06-24" @default.
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- W2349396071 date "2010-01-01" @default.
- W2349396071 modified "2023-09-26" @default.
- W2349396071 title "Relationship between Serum Visfatin and Insulin Resistance in Women with Gestational Diabetes Mellitus" @default.
- W2349396071 hasPublicationYear "2010" @default.
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